BIOL 3306 Lecture Notes - Lecture 4: Skeletal Muscle, Loose Connective Tissue, Myosin
16 Dec 2017
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Muscle fibers (myofibers) fibrils bundle of fibers force. Long multinucleate mydoblasts (fascicles) filaments thin actin thick myosin. Fascicle wrapped in perimysium: both wrapped in fibers. Fiber wrapped in endomysium (areolar connective tissue: muscle, fascicle and fiber are all connected together to tendon. Huxley and huxley: huxley and niedergerker. Structural relationship between a skeletal muscle fiber and its nmj. One fiber is only controlled by one motor neuron. 200-300 vesicles being released of nts: 10 000 molecules of ach, 3-5000 nachr, na+ comes into the channel, then generate change in vm (membrane potential) The structure of a nmj and the generation and propagation of an ap. Action potential spreads along the length of muscle in both directions a the. Propagates through hodgkin-huxley from one end to the other. Embedded in t-tube, there are dhpr: dhpr is basically a calcium channel. Myosin heads can now physically interact with the active sites: cross bridge formation.
