NEUR 1201 Lecture Notes - Lecture 15: Temporal Lobe, Homeostasis, Reticular Formation
23 Mar 2017
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Document Summary
Impairments in short-term memory, attention: mood disorders, depression. Irritability: rapid mood changes, sleep disturbances, memory deficits, decreased verbal & visual memory, lasts up to 7 days after injury, difficulties problem solving, post-concussion symptoms are highly correlated with performance on cognitive tests. Epidemiology of traumatic brain injury: work, military, sports*, construction, automotive, etc. , 15% of soldiers meet criteria, football (high school & collegiate) Impact can be direct or indirect: sport related collision vs. blast exposure. Impact can be linear, rotational or angular (or combination) Direction of force: direction of impact matters, e. g. Linear, rotational or angular: directional forces will dictate presenting symptoms, long-term consequences, extent and rate of recovery, etc. , this makes it difficult to compare concussions between patients (humans) Acute metabolic cascade: concussions lead to an acute metabolic cascade, damage to neural & vascular tissue leading to a distortion of cell membranes (grey matter, white matter & blood brain barrier)
