NEUR 2001 Lecture Notes - Lecture 6: Institutional Animal Care And Use Committee, Belmont Report, Nuremberg Code

• School: Carleton University
• Department: Neuroscience
• Course: NEUR 2001
• Professor: Melissa Chee

Document Summary

Ethical responsibilities: to ensure dignity, welfare & respect for both human & nonhuman subjects, to ensure accurate & honest research conducting & reporting. Institutional animal care and use committee (iacuc) same as (acc: each institution that conduct research with animals will have an animal research review board = iacuc. Review & approving all research using animal subjects. Protect animal welfare by ensuring that all research meets the ethical criteria. Comprised of veterinarian, at least 1 scientist, 1 member of public with no affiliation to institution. Guidelines for animal research 3 r"s: reduction, use fewer animals where possible. Justify the number of animals needed: refinement. Improve care of animals: minimize physical/ psychological distress, enforce early predictors of endpoints (no death, replacement, cell cultures, computer models, use lower sentience animals, epidemiology. 2/3 of participants (cid:862)shocked(cid:863) person until (cid:862)death(cid:863) Reflects how the nazi soldiers obeyed orders in wwii: national research act, belmont report. Outlines basic ethical principles for protecting humans in research.