NEUR 2200 Lecture Notes - Lecture 9: Bioavailability, Cholinergic, Reuptake

• School: Carleton University
• Department: Neuroscience
• Course: NEUR 2200
• Professor: Matthew Holahan

Document Summary

Cholinergic system: controls sympathetic and parasympathetic nervous systems. Fu(cid:374)(cid:272)tio(cid:374) i(cid:374) atte(cid:374)tio(cid:374) a(cid:374)d (cid:373)e(cid:373)or(cid:455) (cid:894)loss of this relates to alzhei(cid:373)er"s(cid:895) Nigrostrailtal path: coordi(cid:374)atio(cid:374) a(cid:374)d (cid:373)o(cid:448)e(cid:373)e(cid:374)t (cid:894)loss duri(cid:374)g parki(cid:374)so(cid:374)"s(cid:895) Mesolimbin path: enhances response to stimuli (reward pathway involved in drug abuse) Evolved with learning by stimulation neurons to change their structure (neuroplasticity) Too much norepinephrine is mania, too little results in depression. Imbalances are associated with ocd, depression, and schizophrenia. Neuropharmacology: looks at drug induced changes in the nervous system. Psychopharmacology: looks at the changes in the nervous system and its effect on behavior and thinking. Drugs: alter the body (food, sunlight, water all alter the body and are all considered drugs) Psychoactive drugs: alter mood, though, and behavior (traditional thought of drugs such as weed, cocaine, lsd) Specific drug effect: based on the biochemical effect a drug has on its specific target in the body. Nonspecific drug effect: behaviors an individual has on the drug (talkative, loud, horny)