NEUR 3207 Lecture Notes - Lecture 3: Leptin, Energy Homeostasis, Anorectic

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Hypothalamic response (all occur at the same time when there is a shift in homeostasis): Humoral response stimulation or inhibition of hormone release (ex. Visceromotor response adjust balance of sympathetic vs. parasympathetic tone. Glucose deprivation is really bad mostly for the brain : you can lose consciousness and death (after ~5 minutes) Your body stores energy in your adipose tissue (i. e. fat) Intrinsic motivation motivation to go get food so that you never run out of energy store. Anabolism building macromolecules like glycogen and triglycerides from precursors. Postabsorption state occurs when energy reserves are broken down (glycogen and triglycerides) to provide body with continuous fuel. **energy homeostasis is working optimally when energy reserves are replenished at the same (average) rate they are expended. Energy reserves are resistant to change and will go back to that setpoint. This suggests that there is communication between energy reserve and brain. Signal proportionate to energy storage reserve leptin lvl = adipose lvl.

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