NEUR 3302 Lecture Notes - Lecture 5: Bupropion, Naloxone, Ejaculation

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Lecture 5 talked about the neurotransmitters that inhibit sexual behaviour: what is the role of serotonin in sexual behaviours - what brain regions are most important for this. 5-ht is responsible for the inhibition of sexual behaviour. When you reduce 5-ht you get an increase in sexual behaviour. Lesions to the rn = faster ejaculations and shorter refractory periods. Mpoa and vmh 5-ht or methystergide (5-ht antagonist) Unreceptive females given methystergide in the vmh and. Mpoa had an increase in sexual behaviour and 5-ht in unreceptive females = floor effect (behaviour was already so low you can"t see an effect) increase in sexual behvaiour and 5-ht reduces sexual behaviour. Receptive females given methystergide in the vmh and mpoa: what are the implications of this for human sexual behaviour (2 experiments, know the results only) Pure ssri (fluoxetine) vs da and ne reuptake inhibitor( bupropion)

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