NEUR 3303 Lecture Notes - Lecture 3: Positron Emission Tomography, Single-Photon Emission Computed Tomography, Statistical Parametric Mapping
25 Oct 2016
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Continuation of lecture 2 lecture #3 (ch. Most widely used design logic in functional neuroimaging comes from the classic reaction time (rt) paradigm time it takes to press a key when a visual stimulus was presented (e. g. a light) Follows a subtraction method similar to today"s neuroimaging. Other aspects of design: averaging many trials to minimize noise artifacts or random confounds, replicating and more replicating, design good tasks and good experiments. Resting states also may involve increased neural activation. Most commonly used neuroimaging techniques are based on 2 types of brain activity: hemodynamic (blood metabolism, electrodynamic (post synaptic electrical activity) Terminology: activity: spontaneous and resting unrelated to task or stimulation, activation: change in activity (generally an increase) due to stimulation or task. Hemodynamic techniques: positron emission tomography (pet) Ct (computed axial tomography) exploits 3d x-ray scanning reconstructions; structures in the body are scanned and then reconstructed through 3d radiation.
