PSYC 2800 Lecture Notes - Substantia Nigra, Tissue Plasminogen Activator, Vascular Dementia
20 Apr 2012
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Document Summary
Stroke: risk factors: age, stroke: an interruption of blood flow either from the blockage of a blood vessel or from bleeding of a vessel. Lack of blood to the brain as a result of stroke. Sets off a cascade of cellular events that cause the real damage to the initial site (where blood vessels feeding onto) and surrounding areas. Change gene expression, protein expression, inflammation, lot of recovery early on: diaschisis. Neural shock that follows brain damage in which areas connected to the site of damage show temporary arrest of function. Stroke - treatment: administer anti-clot drugs. Must be administered within 3 h of stroke! So need to get to hospital right away: neuroprotectants. Drug used to try to block the cascade of post stroke neural events. No good ones available yet: behavioral therapies (e. g. , speech or physical) are often used to facilitate plastic changes in the brain following a stroke, force bad side of body into use.
