PSYC 3403 Lecture Notes - Lecture 3: Alcohol Dehydrogenase, Aldehyde Dehydrogenase, Cannabinoid Receptor

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Depressant used primarily for recreational purposes: really fast crash (dancing then passed out) Second most widely used psychoactive substance in the world. If you double the percentage of the alcohol, that is the proof (ex: 40% alcohol = 80 proof) One drink equivalent 10cc (1/3 oz) of 100% ethanol. Body reduces bac by 0. 015g % in 1 hour. Soluble in both water and fat: moves easily throughout our body (gets through everywhere) Bbb (blood brain barrier) is permeable to alcohol. Crosses placental barrier and enters fetal brain. 95% of alcohol is metabolized by alcohol dehydrogenase. 15% by first-pass metabolism: as soon as you consume, enters your system. Empty stomach vs. food-filled stomach: a full stomach will drain slowly, and allow the alcohol dehydrogenase (in g. i. tract) to break the alcohol molecules down. An empty stomach will drain much faster, and this stops the alcohol dehydrogenase (in g. i. tract) from breaking down the alcohol.

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