BIOL 206 Lecture 22: Lecture 22 (Chapter 11)
19 Apr 2016
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Document Summary
Distinguish between single gene disease and complex diseases. Understand that interactions between our genome and environment make us what we are. Inherited traits and conditions caused by combination of genes and environment. Controlled by 2 or more genes and environment. Genes controlling trait contribute a small amount to phenotype. Environmental factors interact with genes to produce many phenotypes (distribution forms a bell-shaped curve) Person is affected if liability is above a threshold. Multifactorial (complex) traits = polygenic trait + environment component. Single characteristic can be influenced by multiple genes. Individual genes follow mendel"s laws, but are hard to predict. Frequency of distribution of phenotypes forms a bell-shaped curve. Cause slight and often variable range of differences throughout population. Genomes are not only factors that affect traits and diseases. Most traits result from interaction of many genes and environment. Certain environments modify the severity of a disease.
