PSYC 440 Lecture Notes - Lecture 12: Tricyclic Antidepressant, Psychoactive Drug, Selective Serotonin Reuptake Inhibitor

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PSYC 440
Lecture 12 Psychopharmacology
Pharmacology
1. Why is this relevant for psychologists?
a. Many clients are on medication (for mental health or physical health problems):
- How can drugs influence psychotherapy responses?
- How can psychotherapy influence drug responses?
2. Relevant statistics (psychologists)
a. 43% of their clients use psychotropic medications.
b. 87% of practicing psychologists reported they had been involved in some way
(more or less) in the decision to prescribe medication for at least one of the
clients on their caseloads.
c. 7% of respondents indicated they participated in the decision to prescribe for
more than half their patients.
3. Types of medication used for mood and anxiety disorders:
a. SSRIs.
b. Tricyclic antidepressants
c. Monoamine Oxidase inhibitors.
d. Antipsychotics
4. Antidepressants in children:
a. Prescribing antidepressants to children is a complex clinical decision:
- Efficacy has been much less studied (i.e. only very well large clinical trial
studies).
b. 2004:
- Black-Box warning for increased suicide risk in children and adolescents:
i. Yet, idea of increased suicide risk is controversial, and
researchers/clinicians have different opinions:
Systematic reviews of published RCT data, indicated that the use
of newer AD (Selective serotonin reuptake inhibitors, SSRIs; and
selective norepinephrine reuptake inhibitors; SNRI) by children
and adolescents increased the risk of suicidal behavior and should
be closely monitored.
The proportion of children and adolescents prescribed an
antidepressant decreased since 2004, and the rates of completed
suicides among children and adolescents rose significantly.
No significant risk differences between drug and placebo in the
SSRI treatment of depression in children and adolescents.
5. Side Effects vs. Adverse Effects:
a. Adverse effects:
- Unexpected, unintended and unpredictable (i.e. very rare; e.g., severe
allergic reaction, mania after taking an antidepressant).
- Serotonin syndrome:
i. Caused by an overdose or drug interactions.
b. Causes of side effects and adverse effects:
- Patiet’s reatio to ediatio protocol.
- Excessive dosages.
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Document Summary

Lecture 12 psychopharmacology: pharmacology, why is this relevant for psychologists, many clients are on medication (for mental health or physical health problems): Efficacy has been much less studied (i. e. only very well large clinical trial studies): 2004: Black-box warning for increased suicide risk in children and adolescents: Yet, idea of increased suicide risk is controversial, and researchers/clinicians have different opinions: The proportion of children and adolescents prescribed an antidepressant decreased since 2004, and the rates of completed suicides among children and adolescents rose significantly. No significant risk differences between drug and placebo in the. Ssri treatment of depression in children and adolescents: side effects vs. Unexpected, unintended and unpredictable (i. e. very rare; e. g. , severe allergic reaction, mania after taking an antidepressant). Caused by an overdose or drug interactions: causes of side effects and adverse effects: Poor treatment adherence (i. e. the degree to which a client correctly follows treatment advice):

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