PSYC 455 Lecture Notes - Lecture 4: Covalent Bond, Second Messenger System, Frog Legs
17 Feb 2018
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Lecture 4 pharmacodynamics: drug-receptor interactions (pharmacodynamics, definitions, endogenous: Coming from within (e. g. , endogenous ligand; a ligand produced by the body): exogenous: Coming from outside the body (e. g. , exogenous ligand; drugs): ligand: Any molecule that binds to a receptor and makes changes to that receptor (e. g. , drug, neurotransmitter): binding sites, primary binding site: The place on the receptor where a neurotransmitter or drug would normally bind to: allosteric binding site: A place other than the pbs where a drug will bind to: ligand/nt interaction with receptor bonds can be: Weak (e. g. , ionic bonds, hydrogen bonds, vanderwaals bond): Make up most bonds (i. e. thousands of ligands pop-on and pop-off at the same time). If it"s a(cid:374) a(cid:374)tago(cid:374)ist, the(cid:374) it pretty (cid:373)u(cid:272)h o(cid:449)(cid:374)s that re(cid:272)eptor u(cid:374)til the brain makes a new receptor: affinity: The strength of the bond between any given ligand and the given receptor that it binds to:
