BIOC 4403 Lecture Notes - Lecture 37: Transposable Element, Microfluidics, Chromatin
18 Apr 2016
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Document Summary
4403 ii l17 - functional genomics: functional. Integrating all the omics to investigate functional aspects of genes and genomes at every possible level of organization. Focus is large-scale studies on function by taking advantage of advances in areas: levels in. Community: basic methods, why important, two keys to the development of miniaturized platforms for biological assays, electrophoresis on a chip. Biological experiments - high throughput technologies - bioinformatic analysis - results including conclusions on gene, transcript and protein levels. % of genes with inferred function decreases as the complication of the organism increasing. Dna, rna or proteins, generating digitalized data that can be visualized and analyzed: genome-wide studies of gene expression and function, dna microarrays and rna-seq, protein microarrays, chip-seq, mutant library, dna microarrays and rna-seq. Measure gene expression at the transcript level of many genes at a time (e. g. "cancer panel", "immunity panels, etc), or potentially all the genes in an organism"s genome: protein microarrays.
