MICI 2100 Lecture Notes - Lecture 3: Ultrastructure, Cell Envelope, Flagellum
Document Summary
Looking at space-filling models of core rna polymerases from each of the three domains of life reveal some interesting similarities and differences between them. Core rna polymerases from the archaea domain and the eukarya domain have similar shapes. Interestingly, a eukaryotic core rna polymerase can function in an archaeal system in vitro (in glass). The core rna polymerases from the bacteria domain vary significantly in both the placement of orthologous proteins and its overall shape from the core rna. Polymerases of the other two domains of life. On a final note, it"s clear that transcription (dna rna) has evolved different across the three domains of life. Promoter: site on dna, where rna polymerase binds. It drives the expression of a single gene. Bacterial genes don"t: splice dna, have introns. For bacterial genes, both transcription (dna mrna) and translation (mrna protein) occur in the same compartment (cytoplasm) and at the same time.