MICI 2100 Lecture Notes - Lecture 11: Adaptive Immune System, Innate Immune System, Choir Of Young Believers

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The immune responses to both types of infections are different: extracellular : the bacteria live outside of cells. Defence innate immune system and antibodies. Extracellular: case 1 - have not seen the pathogen before. Complement proteins will bind directly to the bacteria. It will attract some of the resident leukocytes in the skin, such as the macrophages and mast cells. Produce reactive oxygen and reactive nitrogen intermediates. Dendritic cells uptake antigens for presentation to present it to your t cells and b cells. Dc will uptake an antigen , process it, and travel to a local draining lymph node. Dc is the link b/w the innate and adaptive immune system. Some give immediate immunity as they see the bug. In the case of plasmacytoid dcs , they immediately produce cytokines , such as type 1 interferon . Extracellular: case 2 - have seen the pathogen before. Also part of innate immune system are natural killer cells .

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