MICI 2100 Lecture Notes - Lymphadenopathy, Mast Cell, C3B
10 Oct 2013
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Engages in surveillance activity against cancer development: mice without immune system, keep them in an enclosed clean environment, they will develop cancer much easier, immuno-deficient people die by other infections disease before cancer. Is mostly non-self reactive but tolerates some self reactivity: hyper active immune systems are reason for immune- deficiency, allows respond to self cells (cells that look like self) Looking too much like self causes immune system to respond to those cells and then attack self. Is tightly regulated: swollen lymph nodes have extra cells used for immune response, this is brought down when you are no longer sick, but doesn t go down to zero because of memory . Because they must somehow provide some kind of protection. (advantage) Transfer of antibody from one individual to another to provide short term protection. Development of an immune response by contact with the offending organism or protein: if you get measles you will develop a long lasting immune response.
