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Class Notes for Microbiology & Immunology at Dalhousie University

MICI 2100 Lecture Notes - Lecture 19: Vaccinia, Influenza Vaccine, Orthomyxoviridae
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MICI 2100 Lecture 19 November 22, 2018 Viral Vaccines Overview History of vaccines How viral vaccines are made Smallpox eradication (Vaccinia virus beats Variola virus) Polio: Sabin vs. Salk vaccines ...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 20: B-Cell Receptor, Adaptive Immune System, Phagolysosome
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MICI 2100 Lecture 20 November 27, 2018 Immunity to Bacterial Infection Phase 2: Adaptive (Specific) Immunity To the right shows a dendritic cell (shown in light gray) is conjugating with T cells. It is an important In T...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 18: Orthomyxoviridae, Virus, Poliovirus
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MICI 2100 Lecture 18 November 20, 2018 Virus Assembly and Egress Ebola Outbreak in the Democratic Republic of Congo Fourth month of an Ebola outbreak Typically, DRC Ebola outbreaks only last 3 months This outb...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 17: Cytotoxic T Cell, Noxious Stimulus, Mast Cell
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MICI 2100 Lecture 17 November 6, 2018 Microbial Recognition by the Innate Immune System According to the Kuby textbook, the listed cells (neutrophil, eosinophil, basophil, and mast cells) are classified as granulocytes....

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 13: Virulence-Related Outer Membrane Protein Family, Influenza A Virus Subtype H3N2, Influenza A Virus
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MICI 2100 Lecture 13 October 18, 2018 Virus Strucutre: Capsids, Envelopes, and Genomes Influenza Virus Structure and Genome Negative sense RNA virus Single Stranded Segmented genome Enveloped virus Sph...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 14: Icosahedral Symmetry, Myelitis, Flavivirus
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MICI 2100 Lecture 14 October 23, 2018 Viral Entry Other Respiratory Viruses Circulating Now Viruses In The News Canadian doctors see spike in limb paralysis among kids CDC confirms 62 c...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture 15: MICI 2100 Lecture 15
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MICI 2100 Lecture 15 October 25, 2018 Viral Genomes I Virus Genomes and Cellular Antiviral Defenses Viruses In The News 7 Children Dead in Virus Outbreak At New Jersey Facility Adenoviruses causes mild to severe illness, t...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 9: Microorganism, Innate Immune System, Epithelium
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MICI 2100 Lecture 9 October 4, 2018 Immune System Overview We live in a world that is teeming with disease-causing microorganisms that include viruses, bacteria, fungi, and parasites. Our survival depends on defense mechan...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture 16: MICI 2100 Lecture 16
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MICI 2100 Lecture 16 November 1, 2018 Virus Genome II Genome Replication Strategies and Antiviral Drugs That Target Replication Whats New With Flu A total of 105 more laboratory detections of influenza were reported. All b...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 12: Intracellular Parasite, Fetus, Serial Dilution
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MICI 2100 Lecture 12 October 16, 2018 Why Study Viruses? Viruses are all around us All living thing encounter billions of virus particles a day Infect all living things, plants, bacteria, insects, vertebrates,...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 10: White Blood Cells (Album), Red Blood Cell, Adaptive Immune System
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MICI 2100 Lecture 10 October 11, 2018 Different immune cells have specific and important roles. In the picture, the red cells are red blood cells. The white blood cells are shown in purple; The ones with polymorphal nuc...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 2100 Lecture Notes - Lecture 11: Chemokine Receptor, Humoral Immunity, Chemokine
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MICI 2100 Lecture 11 October 30, 2018 Humoral Immunity: Cytokines, Complement and Antibodies Humoral immunity is the aspect of immunity that is mediated by macromolecules found in extracellular fluids such as secreted anti...

Microbiology & Immunology
MICI 2100
Thomas N.
MICI 3119 Lecture Notes - Lecture 19: Endospore, Plant Pathology, Permease

1 Types of Solute Uptake Uptake without a transporter o Rates of uptake: o Low o Proportional to concentration o No saturation o E.g. simple diffusion Transporter-mediated uptake o Rates of uptake are proportional to trans...

Microbiology & Immunology
MICI 3119
Lee Song
MICI 3119 Lecture Notes - Lecture 10: Okazaki Fragments, Isotopes Of Nitrogen, Dna Ligase

1 Meselson & Stahls experiment DNA grown in a heavier nitrogen (15N) is transferred to the 14N medium and allowed to divide. After one replication, DNA was found to have an intermediate den...

Microbiology & Immunology
MICI 3119
Lee Song
MICI 3119 Lecture Notes - Lecture 1: Mycolic Acid, Arabinogalactan, Flagellum

1 Lecture 1: Intro Bacterial Physiology the study of structures functions of bacterial cells and their components Overview of a bacterial cell Surface Appendages Capsule, flagella, pili Cell envelope outer membrane, cell ...

Microbiology & Immunology
MICI 3119
Lee Song

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