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Class Notes for Neuroscience at Dalhousie University

NESC 2570 Lecture Notes - Lecture 9: Protein Kinase A, Adenylyl Cyclase, Excitatory Synapse
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They found that the activation of the interneuron influenced the behaviour of the sensory terminal synapsing on the motor neuron ...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2570 Lecture Notes - Lecture 8: Inhibitory Postsynaptic Potential, Reversal Potential, Membrane Potential
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Excitatory Postsynaptic Currents and Potentials Post synaptic currents and potentials are called excitatory postsynaptic currents and potentials (EPSCs and EPSPs) if they increase the likelihood of a posts...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2570 Lecture Notes - Lecture 6: Full Collapse, Cav2.1, Electron Microscope
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Neurotransmitter Release October 21, 2015 1:32 PM Transmitter release from synaptic vesicles Quantal release of neurotransmitters The neuromuscular junction as preparation to study chemical transmission Miniature and plate...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2570 Lecture Notes - Lecture 7: C2 Domain, Syntaxin, Vesicle Fusion
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Munc13 will bind to RAB 3 and RIM It is involved in priming allows for close interaction between interaction between RIM and RAB3 Will also bind to syntaxin and help unfold it in order for it to interact with synaptogravi...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2570 Lecture Notes - Lecture 1: Molecular Motor, Santiago Ramón Y Cajal, Amyotrophic Lateral Sclerosis
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Chapter 1 Neurons and Glia September 12, 2015 12:33 AM Monday, September 14th 2015 Levels of Analysis in Neuroscience Atoms Molecules (protein, DNA, etc.) Individual Cells Pairs of cells connected by synapses Networks of ...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2570 Lecture Notes - Lecture 5: Hyperkalemic Periodic Paralysis, Channelopathy, Hyperkalemia
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Decay of the sodium current is slow, so they don't inactivate correctly Sodium Channelopathy - Hyperkalemic Periodic Paralysis Single sodium channel openings Normal and mutant (hyperkalemic period paralysis) ...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2570 Lecture Notes - Lecture 4: Calcium Channel
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Voltage gated channel, the activation goes up with depolarization if you take a snapshot and step from 60mV to the depolarization, +50 depolarizing step elicited outward potassium current The gating of this potassium curr...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2570 Lecture Notes - Lecture 2: Osmosis, Ion, Resting Potential
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Chapter 2 September 16, 2015 2:31 PM Wednesday September 16th 2015 How can the nervous system carry out its job Translate and modify information so that the organism can respond to its environment We need a nervous system ...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2570 Lecture Notes - Lecture 3: Equilibrium Point, Tetrodotoxin, Axon Hillock
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Membrane Properties September 23, 2015 2:35 PM September 23rd 2015 Action Potential Form and Nomenclature Membrane potential at rest is 60mV This gives way to the rising phase and goes above zero (depolarized less polariz...

Neuroscience
NESC 2570
Crowder Nathan
NESC 2470 Lecture Notes - Lecture 15: Thalamus, Meninges, Continuous Positive Airway Pressure
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Sleep I o Heartbeat occurs in a rhythmic way o Respiration also does but occurs in a longer way then heartbeat o We can change our rate of respiration easier than changing our heart rate. Thus, some biological rhythms are ...

Neuroscience
NESC 2470
Dr.Stamp
NESC 2470 Lecture Notes - Lecture 17: Foxp2, Bonobo, Spoken Language
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Language I o Certain amount of trial and error, much of language is instinctive o You dont necessarily need a comprehension of grammar o Although language fits into a certain set of characteristics, it doesnt have to be so...

Neuroscience
NESC 2470
Dr.Stamp
NESC 2470 Lecture Notes - Lecture 16: Caffeine, Delta Wave, Brainstem
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Sleep II o Sleep is consisted of lack of response to the environment and interaction o More or less universal every species requires sleep, however they do it for different periods of time o We spend 13 of or life sleepin...

Neuroscience
NESC 2470
Dr.Stamp
NESC 2470 Lecture Notes - Lecture 9: Reticular Formation, Motor Neuron, Vestibulospinal Tract
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Motor Systems I o Automatized motor control of playing guitar while singing o Rodrigo Y Gabriela o All of this is due to practice because their nervous systems are no different than ours o Each level of the motor system ha...

Neuroscience
NESC 2470
Dr.Stamp
NESC 2470 Lecture Notes - Lecture 13: Classical Conditioning, Thalamus, Autonomic Nervous System
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Emotion I o Operationally define shit- defining emotions is difficult o It has an impact on behaviour o Operational definition meaning that o Two definitions that are not ...

Neuroscience
NESC 2470
Dr.Stamp
NESC 2470 Lecture Notes - Lecture 14: Libido, Temporal Lobe, Lobotomy
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Emotion II o Phineas Gage had an unfortunate accident that lead to personality changes that caused his lack of ability to regulate his emotions o Darwin Theory of emotion consistency of emotion throughout the animal kingd...

Neuroscience
NESC 2470
Dr.Stamp

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