Class Notes (811,169)
Canada (494,539)
Nursing (97)
NURS 2090 (20)

Clinical Models of Altered Cellular Proliferation and Differentiation.docx

5 Pages
Unlock Document

Dalhousie University
NURS 2090
Heather Helpard

Clinical Models of Altered Cellular Proliferation and Differentiation Lung Cancer Pathophysiology  Leading cause of cancer deaths worldwide  Smoking and industrial exposures often implicated  Tumors originate most frequently in the epithelial lining of the bronchi, bronchioles, and alveoli  4 subtypes: adenocarcinoma, squamous, large, and small cell carcinomas Clinical Manifestations  Persistent cough  Hemoptysis  Chest pain  Shortness of breath Staging of Lung Cancer Diagnostic Criteria  Bronchoscopy  Chest x-ray  Tissue biopsy/cytology  MRI/CT/Ultrasound  Carcinoembryonic antigen (CEA)  Lung Cancer Treatment  Based on tumor type Small cell carcinoma  Chemotherapy  Non-small cell carcinoma  Surgery  Chemotherapy  Radiation, if surgery not feasible Colorectal Cancer Pathophysiology  Multiple lifestyle risk factors  Disruption of p53 gene implicated in 3 of 4 cases of colorectal cancer  Cellular transformation in mucosal epithelium of the bowel begins at the base of the crypts Clinical Manifestations  Change in bowel habits  Occult or frank blood in stool  Abdominal pain  Bowel obstruction  Anemia Diagnostic Criteria  Digital rectal exam  Colonoscopy Treatment  Surgery  Chemotherapy  Radiation Brain Cancer Pathophysiology Metastasis much more common to brain than primary tumors (10:1 ratio) Primary tumors originate from:  Glial cells  Meninges  Schwann cells  Ectopic tissues Clinical Manifestations  Headache  Vomit
More Less

Related notes for NURS 2090

Log In


Don't have an account?

Join OneClass

Access over 10 million pages of study
documents for 1.3 million courses.

Sign up

Join to view


By registering, I agree to the Terms and Privacy Policies
Already have an account?
Just a few more details

So we can recommend you notes for your school.

Reset Password

Please enter below the email address you registered with and we will send you a link to reset your password.

Add your courses

Get notes from the top students in your class.