Importance of cells in bone growth, remodeling and repair.docx
Importance of cells in bone growth, remodeling and repair
Osteoblasts - bone-forming cells (cartilage to bone)
Osteocytes - mature bone cells that maintain bone structure derived from
Osteoclasts - bone-absorbing cells
Chondroytes - cartilage forming cells
How does bone develop?
Intramenbranous ossification: bone development between sheets of fibrous
connective tissue: used in flat bones
Endochondrial ossification: cartilage is replaced by bone, used by most bones
How do hormones affect bone growth?
Growth Hormone (GH) - stimulates general bone growth and the epiphyseal plates
Sex hormones - increase growth during adolescence
Vitamin D- converted to a hormone to allow calcium absorptions What is bone remodeling and what is the role in homeostasis?
- Bone remodeling
- Remodeling allows bone to respond to stress
Regulates the calcium in blood through hormones
Osteoporosis - bones are weakened due to a decreased bone mass
formation of blood clot -> formation of cartilaginous callus -> formation of bony
callus ->bone remodeling
- invades and forms cartilaginous callus
Hematoma ( blood clot )
The axial skeleton
- skull - made of cranium and facial bones