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Immune Function.docx

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Langara College
KINS 2295

Immune Function  All animals have innate immunity. It is a non-specific mechanism that provides a rapid response to a pathogen. They don’t adapt to previous attacks.  Barrier defence (ex. Skin and membrane lining of our organs) it stops the pathogen from entering the body. If the pathogen enters the body, the body can distinguish between their cells and pathogen and kill it.  Molecule recognition is specific receptors that recognize molecule in pathogen such as LSP and peptidoglycans by using toll-like receptors.  It can lead to other responds such as inflammation of the area, or fever.  TLR have small amounts of receptors on the cell membrane that can recognize many conserve chemical in virus such as LSP and peptidoglycan that animal cells don’t express.  TLR3 recognize double strand RNA, TLR4 recognize LSP, and TLR5 recognize bacterial protein to make their flagellum.  Hemocytes are equal to white blood cells that circulate in their fluid.  First the phagocytic must recognize there is a pathogen, and then it engulfs the pathogen by endocytosis forming vacuole. Then the lysosome will come in the fuse with the vacuole spilling its digestive enzyme into the vacuole killing the pathogen. After it spits it out though exocytosis.  Since the lymphatic system picks up all the loss of water and material and return it back to the circulation system. Phagocytes cells can clean the blood because it has the lymph node that stores a lot of phagocytes.  It creates swelling in the area that recruits a lot of phagocytic to kill the pathogen when it enters the skin. It ha
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