PHED-4547EL Lecture Notes - Lecture 13: Hematopoietic Stem Cell, Oncotic Pressure, Bone Marrow

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Chapter 13 the hematopoietic and lymphatic systems. Transport substances to tissues: oxygen, nutrients, hormones, leukocytes, erythrocytes, platelets, antibodies, co2 and other waste products of cell metabolism to the excretory organs of the body. Volume of blood: about 5 l, but varies according to size of individual. Almost half of blood consists of cellular elements suspended in plasma (viscous fluid) Stem cells: precursor cells in bone marrow that differentiate to form erythrocytes, leukocytes and platelets. Cellular elements: erythrocytes, leukocytes, neutrophils, monocytes, eosinophils, lymphocytes, basophils, platelets. Albumin is a protein in plasma that provides colloid osmotic pressure in blood (helps keep fluid in the blood vessels. All blood cells arise from pluripotential hemopoietic stem cells: differentiate in the bone marrow to form, lymphoid stem cells which are the source of lymphocytes, progenitor cells which are precursors to erythrocytes, non-lymphoid leukocytes and platelets.

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