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Class Notes for Mathieu Roy

MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture 17: Lecture 17 - Molecular Genetics Techniques

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8 Jun 2016
7
De nition: group of organisms produces from one stock or ancestor. Easy to misunderstand because it can mean slightly different things in different sit
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 25: Aminoacyl-Trna, Start Codon, Transfer Rna

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8 Jun 2016
8
How is the information content in dna transcribed to produced rna: genetic code: speci es which amino acids will be used to build a protein, codon: a s
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture 31: Lecture 31 - Functional Genomics & Proteomics

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8 Jun 2016
12
Make a vector with anking t7 rna pol promoters that drive transcription of a region between them that investigators inserted a sequence that correspond
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 26: 28S Ribosomal Rna, Peptide, Polyadenylation

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8 Jun 2016
9
Energy from gtp hydrolysis promotes a conformational change in the ribosome. Upon binding of the ternary complex in the a site, ef1 alpha is released a
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 28: Transferrin Receptor, Sequence Motif, Granulocyte Macrophage Colony-Stimulating Factor

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8 Jun 2016
7
Lecture 28 - regulation of gene expression mrna stability. The stability of cytoplasmic mrnas varies widely within and between organisms: mrnas can be
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture 5: Lecture 5 - DNA Replication

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8 Jun 2016
8
Mutations in protein coding regions can be lethal therefore dna replication has to occur at a high delity. Dna replication proceeds through a semiconse
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 7: Restriction Enzyme, Dna Ligase, Molecular Cloning

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8 Jun 2016
7
Dna sequencing: there are fundamental techniques in molecular biology. Other more complex techniques borrow from the same general principles underlying
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 3: Pyrimidine, Regular Sequence, Polynucleotide

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8 Jun 2016
8
Backbone is composed of repeating phosphate-pentose units. Contains no information; it"s too regular (repeating sugar and phosphate) There is an end to
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 12: Dna Barcoding, Sea Slug, Non-Coding Rna

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8 Jun 2016
7
Originally free organisms that were endocytosed and became endosymbionts. Resemble prokaryotes in terms of their genomes: circular, genes typically lac
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 22: Carboy, Transcription Factor Ii H, Protein Kinase

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8 Jun 2016
17
Repeat: ysptsps: numbered 1-7, during transcription initiation the protein kinase associated with tfiih will phosphorylate position/searing 5. Triggers
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 21: Homeobox, Leucine Zipper, Homeosis

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8 Jun 2016
5
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MCGILLBIOL 200Mathieu RoySpring

BIOL 200 Lecture Notes - Lecture 11: Segmental Duplication, Gene Duplication, P Element

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8 Jun 2016
8
There is a negative correlation between transposon mobility and tness: more transposon mobility = more mutants -> knock out genes -> tness drops. Spont
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Mathieu Roy (40)