BIOL 200 Lecture Notes - Lecture 4: Adenosine, Ribonucleoside, Phosphodiester Bond
Document Summary
Melting temperature: half maximum is the hyperchromic shift. Can interact with motifs that have those characteristics. Fibrous proteins: mediating protein-protein interactions dimerization domains, efhand/helix/loop-helix binding with calcium, has ionic changes in itself to trigger protein reactions (conformation change) that take place in specific proteins. Makes a pocket that allows the protein to interact because of ca. 2+binding proteins: zinc finger uses histinies and cystines that are critical because of their folding, they coordinate zinc ions. These proteins are important in binding dna and certain rnas. Its responsible for binding to nucleic acids: domains, large stretches of amino acids, give rise to functional regions of the protein, domains are larger amino acids stretches that fold into specific functional regions. To serve as blueprint for the rna sequence: ribonucleotides. To serve as monomers for rna polymerization: rna polymerase. To catalyze the synthesis of rna: promoter. Tells rna polymerase where to transcribe: template strands (sense)
