BIOL 200 Lecture Notes - Lecture 15: Cluster Analysis, Adenosine, Deoxyribonuclease
Document Summary
Processed pseudogenes (cid:120) mobilized protein-coding genes (cid:120) originate from a reverse transcribed mrna (cid:120) usually a random rare event (cid:120) Lack introns and control regions: because they are using mrna as a template, the(cid:455) do(cid:374)"t have control regions no promoters or cis-regulatory factors (cid:120) most are not expressed. Dna transposons vs. retrotransposons (cid:120) dna transposon (cid:198) cut and paste mechanism (cid:120) retrotransposon (cid:198) retrotransposition (cid:120) (cid:120) dna transposon is cut and paste while retrotransposon is transcribed and rna intermediate is reverse transcribed. 99% are dead. (cid:120) retrotransposons are extremely diverse. Spacer dna (cid:120) simplistic term meaning we do(cid:374)"t k(cid:374)o(cid:449) (cid:449)hat it is. (cid:120) a lot is probably ancient transposable elements that slowly degenerated over the years. (cid:120) fate of a dead gene it will degrade sequence-wise. Lecture 11 the walking dead: transposons and evolution (cid:120) negative correlation between transposon mobility and fitness. If aligned improperly, there is an unequal crossing over.
