CHEM 181 Lecture Notes - Lecture 3: Polyunsaturated Fat, Hypercholesterolemia, Ldl Receptor

• School: McGill University
• Department: Chemistry
• Course: CHEM 181
• Professor: Ariel Fenster

Document Summary

Many trials took place to try to answer the questions above. For every 1% decrease in cholesterol the risk of heart attack is decreased by 2% - cppt trial. This means that you have to treat 67 men aggressively to save one cardiac event. Not trivial, but not as effective as it sounds in percentage. Ldl decreases in response to the use of statin drugs. 100% reduction in cardiovascular events in men who are at risk because of high c-reactive protein levels. It appears that lowering cholesterol can help prevent heart attacks, but not a very significant amount. Total cholesterol should be below 200 (5. 2 on mmol scale) and should not be. Mmol/l = mg/dl x 0. 0113 above 240 (6. 2) Ldl should be below 130 (3. 4) and less than 160 (4. 1) Hdl should be more than 60 (1. 56) and no less than 40 (1. 0). Triglycerides should be less than 200 (2. 26) and less than 400 (4. 52).