ANAT 261 Lecture Notes - Dense Irregular Connective Tissue, Keratin, Loose Connective Tissue

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The skin is divided into three distinct layers: Epidermis the epidermis is stratified squamous epithelium (keratinized: know this, every word is required for describing an epithelium, so be careful to include it all, even the keratinized". No blood vessels in the epidermis cellular layers of the epidermis: stratum germinativum/basale: single layer of columnar cells innermost layer of epidermal tissue, adjacent to the dermis rests on the basement membrane (bm) *note: in the lab, you can"t see the bm structurally, but you know that it is always present between the epidermis and dermis. Actively dividing to provide the cells for the upper layers: stratum spinosum: polygonal cells with central nuclei. Cells interconnected by desmosomes which appears like little spines: stratum granulosum: squamous (flat) cells. Contain keratohyaline granules: granules are basophilic (give cells dark blue/purple appearance) Cells no longer dividing and are committed to death: stratum corneum: dead squamous cells (no nuclei are present) top layer.

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