BIOL 112 Lecture Notes - Lecture 16: Mendelian Inheritance, Color Blindness, Wild Type

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BIOL 112 Full Course Notes
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BIOL 112 Full Course Notes
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Red-green colourblindness: occurs in of children of unaffected parents (recessive) However, actual ratio is 50% female normal, 25% male normal and colourblind. Y chromosome always has recessive allele because it has no gene for colour blindness. If sex and colour blindness assort independently, you would expect the following progeny. Wild type: predominant allele (>99%) in population. Mutant allele: change from the wild type allele, typrically result of recent mutation, also can refer to allele that causes disease. Polymorphic allele: and allele present in >1% of the population. Law of independent assortment only applies to genes on different chromosomes. Take example of fruit fly vestigial vs normal wings and grey vs black colouring. Cis indicates dominant alleles are on two different homologs. Recombination occurs at random points on the chromosome. Therefore probability or rate of recombination between two genes depends on how far apart genes are on the chromosome.

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