BIOL 200 Lecture Notes - Lecture 9: Inverted Repeat, Selfish Dna, Transposable Element
11 Aug 2017
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Document Summary
Interspersed repeated dna sequences that can move in the genome, jumping genes . Also known as transposons, or mobile dna elements. Ultimate form of selfish dna as they propagate at apparent detriment of the host. Can be classified into two basic types based on mode of mobility. Consists of inverted repeats flanking protein coding region (transposase gene) in between. Tir = terminal inverted repeat, terminal region at one end of strand is reverse complement of the sequence at the other end. Target site direct repeats or target-site duplications (tsd) are found just outside of tir. Proceeds through a cut and paste mechanism. Element excises from its original location and inserts into another genomic location. Transposon not integrated into genome, can integrate into any other part, can be anywhere: transposase is expressed and identifies the ends of the. 3" ends to 5" end of transposon: this creates direct terminal repeats upon insertion (not part.
