BIOL 200 Lecture Notes - Tata Box, Tata-Binding Protein, Base Pair

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11 Nov 2013
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Dna and rna are linear polymers of monomers called nucleotides. Pentose phosphate backbone deoxyribose (dna), ribose (rna) hydroxyl in 3" end engages in polymer nucleic acid polymers are directional: free 5" phosphate group free 3" hydroyxl group. Phosphodiester bonds link the groups (one from each base) together. Cg: 3h-bonds, more stable at: 2 h-bonds you can move around dna along longitudal axis b/c no h-bonds formed (no spacing) beta dna: in humans, classical form . Rna can interact w/ dna: a dna = less helical turns than in b dna proteins can regulate dna transcription through morphology (binding to dna) Necessary for dna to be packed in chromatin. In euk: transcription for those genes require tbp binding to their promoters. Promoter region (a-t rich b/c weaker bonding) disordered dna strands absorb more uv light b/c they"re not stacked. Topoisomerase i makes a nick in one strand and then re-ligates it (top.

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