BIOL 201 Lecture 22: Adhesion & the Matrix
19 Apr 2018
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Cells can interact with their environment through chemical signals & physical connections. Physical: microvilli connected from cell to cell through proteins like cell adhesion molecules to transport things through. Chemical: cells can secrete hormones that bind to other cell surface receptors triggering changes in the receiving cell. Cells can stick to one another in their surroundings through cell-to-cell adhesions. Can also stick to the cell matrix through cell-to-matrix adhesions. Cells express a wide, diverse range of cell adhesion molecules (cams). Cells create cell-to-cell adhesions from adding individual, weak interactions which eventually lead to a strong interaction. Each patch is on a separate membrane which attaches to another patch. Cell-to-cell adhesion can sort out cells of different types into separate clusters. Ground up sponge of the same type eventually form back its structure. But, grinding up 2 different sponges caused each type to form their own clusters; they didn"t reform by coming together.
