BIOL 201 Lecture Notes - Rigor Mortis, Endoplasmic Reticulum, Duty Cycle

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Muscles are made up of millions of contractile bundles. chemotactic gradients create zones of rho activity, rho is responding to the gradient. Start at cdc42 (where there"s a lot of cyclic-amp, so there"s a lot of cdc42). Rho needs to be able to be free to get the job done, so if this wave keeps on going the back end will start creating lamellipodia. Sarcomeres are the basic unit of the sliding filament theory. They looked at both em images of contracting muscles and isolated myofibrils and watched them contract under microscope. They saw the thickness of the a band or thick band didn"t change. As the muscle contracted, the length of the i band and sarcomere got shorter. interdigitating filaments. Sarcomeres are tightly packed arrays of actin and myosin filaments and undergo rapid contraction under muscle stimulation. 5-10ms latent period between signal from brain and start of contraction. 40-45ms contraction phase from fully elongated to fully contracted.

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