BIOC 311 Lecture Notes - Lecture 23: Glucagon, Gluconeogenesis, Glycogen

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*fatty acids cannot pass across blood brain barriers to feed brain. 2- glucose from glycogen stores breakdown via liver for 24h/1 day. 3- glucose from gluconeogenesis in liver for up to 30-40 days. Even if drop to 3 mmol need to keep constant for brain. Cell 2 from tissue b = pick up hormone. A- insulin = peptide hormone released when glucose level high ex: after meal. With insulin = most cells take up glucose & without insulin = most cells not take up glucose. B- glucagon - glucose gone = peptide hormone released when glucose level low ex: fasting. With sensors for tight regulation of hormone production. *affects many tissues but maintly #1 liver to feed glucose into bloodstream. Epinephrine = peptide hormone released when glucose level low ex: fasting * like glucagon. Adrenaline made by 2 adrenal glands above kidney. *affects many tissues but maintly #1 muscle to promote glycogen breakdown for fuel.

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