BIOC 312 Lecture Notes - Vas Deferens, Proteasome Inhibitor, Conformational Change
Document Summary
Differs from prokaryotes which are considered to be bags of proteins and dna: properties of eukaryotes, chromatin is segregated from the protein synthetic machinery, chromatin has two different strcutres: Heterochromatin (dark) which is silent: rna is exported out of the nucleus through pores and undergoes, matabolic pathways are compartmentalized allowing for execution of translation different functions: Proteins that go to the er only go to the er, they do not usually go to the nucleus or mitochondria. Some proteins are partitioned between two organelles, but there is a different underlying mechanism. This relates to common proteins that are found in several organelles. Deals with the problem of partitioning an extremely hydrophilic protein between/through a for this: thermodynamics: hydrophobic lipid bilayer bilayer. Protein must translocate this membrane in order to become part of the organelle or insert into the: evolution has had to deal with specificity and thermodynamics. Mechanisms have evolved to take these into account.