CHEM 182 Lecture Notes - Lecture 12: Genzyme, Olanzapine, Mmp1

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20% canada, 25% quebec(highest province), 16% of bc (lowest) smoke. 35. 5 yukon, nwt 35. 7% and nunavut 61. 3% smoke. Tobacco discovered by columbus on november 12, 1492- described as drinking tobacco. Tobago island is said to be first import location of tobacco (origin of name). Active ingredient is nicotine- name from jean nicot (introduced tobacco to france and then to rest of europe). At time any new plant from different country thought to have healing properties. By bridges of london, tobacco resuscitator (1774) for reviving person apparently dying (eg. had drown). Initially tobacco was smoked in pipes (very long stand- remove some of harshness of smoke. Initially was not inhaled) in smoking dens (didn"t smoke alone). Women would snuff tobacco (put it up nose- idea lining of nasal passage very thin and tobacco could be absorbed). 18th century- chew tobacco (us, time of lincoln, spit it out after in spittoons). La cometa (goya painter- first representation of cigarette).