EDKP 395 Lecture Notes - Lecture 9: Sarcomere, Vo2 Max, Macrophage
17 Dec 2012
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Document Summary
Structural proteins provide protection against mechanical stress (hold the muscle structure together) Extends from 1 z band to the other. Maintains sarcomere when all other contractile proteins are removed interacts with actin filament. Force dependent shortening of titin"s spring length. Exosarcomeric proteins: intermediate filament proteins associated with sarcolema (muscle membrane itself) Maintains normal registry of adjacent myofibrils and their relationship to other structures in cell. Membrane- associated proteins: dystrophin, ankyrin, spectrin, vinculin, talin. The two above help hold things together. Allows the msucel cell to withstand daily stresses and wear/tear that they experience with muscle contractions. Type of exercise: ex. eccentric- active lengthening. Typically do during breaking actions- ex. lowering a weight, walking down stairs. Prolonged duration: increased risk of injury with longer workouts. Muscle soreness and edema: max. at 48 hrs post-exercise. Weakness, esp. at low stimulation frequencies: called low frequency fatigue . Elevated serum levels of muscle cell proteins: creatine kinase, myoglobin. Exercise stimulus: siginificant decrease in strength.
