EDKP 395 Lecture 20: EP Lecture 20
27 Mar 2018
School
Department
Course
Professor
Document Summary
Pulmonary physiology of exercise 6 & acid-base balance. Respiratory muscle unloading using a mechanical ventilator increased exercise endurance time (tlim) by ~15% during heavy- intensity constant-load cycle exercise in healthy humans. Conclusion: the work of breathing normally incurred during sustained, heavy-intensity exercise has a significant negative influence on exercise performance. Respiratory muscles have a metaboreflex, they respond to any metabolic stress in the muscles. Respiratory muscle work compromises leg blood flow during maximal exercise. Systematically evaluated them under normal control conditions and then unloaded their respiratory muscles and then loaded the respiratory muscles (at different times) Experimentally increased the work of breathing above the control value and they experimentally decreased the work of breathing below the control value. Lvr: respiratory muscles become overloaded, increase in activation the sns, increases vasoconstriction of peripheral system which decreases vascular conductance. Lbf: muscle more constricted = less blood flow. O2 uptake of leg muscles: less blood flow = less.
