EXMD 509 Lecture Notes - Lecture 2: Gastroesophageal Reflux Disease, Hiatus Hernia, Iron-Deficiency Anemia

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Dysphagia: difficulty swallowing, can be due to anxiety this is a globus sensation, can also be related to acid the minute acid hits the oes, spasming can occur (30% pts) Non-cardiac chest pain: retrosternal chest pain radiating up to the jaw and down both arms, this person appears to be having an acute mi but blood work is normal. Eosinophilic oesophagitis: oes gets infiltrated with eosinophils leading to difficult swallowing, rarer cause of odynophagia. **50mg iv fentanyl + midazolam for sedation prior to upper gi endoscopy. Les straddles diaphragm (2cm above and 2cm below) Antrum = favoured spot for damage (will see in next lecture) Used to visualise the upper git, biopsy and make diagnoses. Yield of standard gastroscopy >80% bc they are only performed for selected cases. Structural disorders: cervical osteophytes bone spurs impinging on the ues, large thyroid enlarged thyroid can push on the ues.

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