EDKP 292 Lecture Notes - Lecture 39: Mesolimbic Pathway, Reticular Formation, Cyclic Guanosine Monophosphate

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We have taste pours on our tongues that contain taste buds. So, the molecules that are dissolved in the saliva will enter through the pore and activate the transduction process. Only na+ molecules will give us a salty taste. Sour tastes are activated by sodium and hydrogen ion channels. Sweet tastes are activated by glucose and they cause g protein cascades and cyclic gmp to increase. Bitter tastes are activated by many mechanisms. The gustatory nerves do not cross, they are ipsilateral. Molecules dissolve in the mucus and then bind to the receptors in the olfactory epithelium. These connect to the receptor cells and travel through the olfactory nerve all the way to the olfactory bulb. The process of transduction is as follows: odour binds to the receptor cells, activates a g protein cascade, activates adenyl cyclase, increases cyclic gmp, ion channels open. Olfactory bulb projects everything into the limbic system.

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