EDKP 485 Lecture Notes - Lecture 3: Croatian Radiotelevision, Shortness Of Breath, Lactic Acidosis

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Respiratory mechanical response to exercise in copd: changes in static and dynamic lung volumes can in some ways impose a mechanical limitation to breathing, particularly in an individuals ability to expand. In copd where all they want is more time to exhale, the disease forces them to breath faster and faster: the mechanical restriction forces copd people to breath more quickly to support an increase ventilatory requirement. In copd, their reduced ic at rest is further reduced in the majority of patients in the rest to exercise transition by dynamic lung hyperinflation. In copd compared to health, the rv is elevated, the tlc is elevated (statically and chronically hyperinflated), the eelv is elevated (gas trapped and static lung hyperinflation) In contrast to the healthy subjects where they go from resting breath (grey) to exercise where they dynamically decrease eelv so that vt expands on the linear portion of the curve.

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