LSCI 204 Lecture Notes - Lecture 20: Metar, International Nomenclature Of Cosmetic Ingredients, Sulfur Mustard

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Mutations are inherited alterations in the dna sequence. A mutation is defined as an inherited change in genetic information; the descendants may be cells or organisms. Mutations: sustainer of life and cause of great suffering: source of all genetic variation, which further provides the raw material for evolution, source of many diseases and disorders. A fly without a heart: a few rare mutant fruit flies never develop a heart and die at an early embryonic stage, tinman gene: a gene that specifies the development of a heart. The two basic classes of mutations are somatic mutations and germ-line mutations. Germ-line mutations arise in cells that produce gametes: a germ-line mutation can be passed to future generations, producing individual organisms that carry the mutation in all their somatic and germ-line cells. Types of gene mutations (based on their molecular nature) Increase in the number of a copies of a set of nucleotides.

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