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MIMM 214 (104)
Lecture 34

MIMM 214 Lecture 34: B cell Development & Tolerance
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Department
Microbiology and Immun (Sci)
Course
MIMM 214
Professor
Claire Trottier
Semester
Winter

Description
B cell Development Tolerance Thursday, April 6, 20176:10 PM Selfreacting B cell (reacting to bone marro) > either apoptosis, or recept diting B cell that selfreacts to soluble self molecules > does not get negatively selected, but becomes ANERGIC once in periphery (nonresponsive) Last column: a B cell thats inept but has escaped the negative selection. Appears as a normal mature nave B cell, but is clonally ignorant.(Nonresponsive) May get activated later on
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