Monday, March 20, 2017 5:24 PM A) The results (graphs) show an increased level of b Tet in CD4+ cells in infected mice, compared to mock mice. i. Similarly, increased level of Granzyme B in CD8+ cells in infected mice, compared to mock mice. B) Conclusions: Tbet is a master regulator for TH1 cells. Granzyme B is part of the cytotoxic granules in CD8+ cells and can cause apoptosis in CD8+s target cells. Therefore, we see that TH1 and CTL are involved in clearing Zika virus.