PHAR 301 Lecture Notes - Lecture 16: Arvid Carlsson, Atypical Antipsychotic, Positron Emission Tomography
23 Mar 2016
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Atypical antipsychotic = second-generation (i. e. little or no eps, little or no increase in prolactin, little or no tardive dyskinesia) Neuroleptic (an antipsychotic that produces eps, especially catalepsy) Nucleus accumbens (main terminal area for mesolimbic da pathway) Brody chapter 29 - treatment of psychotic disorders. Do not neglect the part about side-effects. He was a well-known illustrator in the victorian error. Debate: there is a broad spectrum for this disorder; some people have only positive symptoms, others have both positive and negative, etc. It"s fundamentally a thought disorder which causes emotional withdrawal. Increase in the size of the ventricular space in the brain. But it"s not a suitable biological test for schizophrenia because other disorders can show the same symptom: disordered (da, neurotransmission) Your lifetime risk of schizophrenia is much higher if a close relative has the disease. There is no biological test for schizophrenia; it is based on questionnaires and interviews.
