PHAR 301 Lecture Notes - Lecture 20: Bone Marrow Suppression, Cytochrome P450, Cisplatin
Document Summary
In canada, 1 in every 2. 2 men and 1 in every 2. 4 women have a lifetime probability of developing cancer. >1 of every 4 canadians will die from cancer. 30% of the cause of death in canada is attributed to cancer. Three types of cancer account for the majority of new cases in each sex: prostate, lung, and colorectal in males and breast, lung and colorectal in females. Lung cancer remains the leading cause of cancer death for both men and women. Overall, colorectal cancer is the second leading cause of death from cancer. The net result is the alteration in regulation of cell proliferation and differentiation. Some kind of dna damage or alteration in dna sequence may be important in developing cancer. Thickening or a lump in breast or elsewhere. Obvious change in a wart or mole. There are two different kinds of growth: exponential growth (keeps increasing, gompertzian growth (plateau)