PHGY 209 Lecture Notes - Lecture 13: Iron-Deficiency Anemia, Hereditary Spherocytosis, Etiology
16 Sep 2016
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And that is all that it does need, to transport oxygen, indeed! (it also carries some co2, Derived from stem cells in the marrow, its committed pathway is quite narrow: Its maturation"s quite exotic, it gets smaller and pyknotic (shrivelling of nucleus) Its lifespan"s short, in blood it stays, a mere one hundred twenty days. You"re one cool cell, we all agree! delightful sight, than that of an erythrocyte: dumbbell-shaped and quite mobile, it has its individual style. Unlike all other types of cells, it is devoid of organelles. No ribosomes, no nuclear matter, just some solutes, dissolved in water. Decrease in the oxygen-carrying capacity of blood 1) rbc count . ~33% (how much hemoglobin there is in each cell) Etiologic classification of anemia: diminished production, abnormal site aplastic (hypoplastic) anemia . Normochromic: abnormal stimulus stimulation failure . Inadequate raw materials iron deficiency anemia (most common type) etiology: Requirements (infancy, adolescence, pregnancy) need for more red cell production.
