PHGY 210 Lecture Notes - Pituitary Stalk, Protein Precursor, Cortisol

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Lecture 1 - endocrinology (part 1 of 6) Endocrine signaling always involves a hormone that is secreted into the blood stream by an endocrine gland. As we will see, there are glands in the body that are really dedicated endocrine structures. However, essentially any cell in the body can send out a signal that effectively, is hormonal in nature. So you have a hormonal signal that is released and is transported through the bloodstream to it s target (distant target site). It s target is whatever cell happens to have the receptor for that particular hormone. This gure also shows cascades of hormonal signalling - ie. you ll have a primary endocrine organ which signals to a secondary endocrine organ which will sometimes even signal to a tertiary endocrine organ. Neuroendocrine signaling - a variation on any type of endocrine signal except the hormone releasing cell is a neuron. Gure to the right, the hypothalamus is talking to the pituitary.

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