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PHGY 209 (410)
Ian Gold (2)
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Immunology.docx

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Department
Physiology
Course
PHGY 209
Professor
Ian Gold
Semester
Fall

Description
October 4, 2013 PHGY-209 T-Cell notes TH2 : humoural response (bacteria) TH1: cellular response (viral) Anti-cell receptors are anti-self, only 5% cells leave thymus/marrow because 95% are cyto-toxic Regulatory T-cells downregulate to maintain tolerance CD4+ helper cells are pro-inflammatory and are polar to Th17 bowel can distinguish between foreign and dangerous and those that are not -maintain suppression of materials that are foreign and not dangerous follicular B are in the lymph node and help in immune system Viruses don't live in dendrites, only inside cells where they take over cellular processes -genome taken over by virus, which in turn, makes more viruses Dentritic cell digests virus like it is a bacteria MHC class II molecule TH1 helper cell (cellular) has T-cell receptor specific for peptide Tcd8+ cell -no linkage between T and B cells or of the cyto-toxic and dendritic cell interferon, INF (for inflammation)... cause maturation and proliferation of C cell Bring in infected cell
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