PHGY 210 Lecture Notes - Lecture 5: Antiestrogen, Breastfeeding, Endocrine System
25 Feb 2013
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Unlike the males, the females have several positive feedback loops. Lh and fsh stimulate follicular receptor development, which then ups estrogen. Estrogen then makes follicles more sensitive to gonadotropin hormones. Progesterone and estrogen levels from the previous cycle drops off. Negative feedback loop ups fsh levels from pituitary. By day 8, only 1 follicle remains to further develop. Reduce feedback fsh release, but increases gnrh receptors on the pituitary, to increase lh production. Lh accumulates to a very high level within the pituitary. Oral contraceptives the pills contains estrogen and progesterone, maintains a leveled level of estrogen and progesterone, which supress lh and fsh release. The corpus luteum under lh increases levels of progesterone. If fertilization does not happen in 14 days, the corpus luteum degenerates, levels drops and the endometrium degenerates as well. Restarts cycle as fsh levels are upped while everything else becomes low. The egg, when released, it goes down the fallopian tube.
