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Endocrinology- Lecture 1

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McGill University
PHGY 210
Ann Wechsler

thLecture One Monday January 4 2010thMIDTERM EXAM Monday March 8 630pm800pm 30 MC 30ENDOCRINOLOGYEndocrinology is self attenuating eg negative feedback loopsThe essence of endocrinology its all about communicationCOORDINATION OF PHYSIOLOGICAL PROCESSESIn a living organism there must be coordination of number of physiological activities taking place simultaneously such as movement respiration circulation digestion excretion and metabolism Endocrine system and Nervous system both signal anatomical parts of the bodyThe central nervous system and the endocrine system represent the two major means by which these functions are coordinatedLONG DISTANCE COMMUNICATIONCommunication between cells that are not in contact is achieved through a number of chemical substances hormones which are secreted by releasing cells and interact with specific receptors on distant target cells bind to them Signaling through these receptors leads to a specific physiological effect Cells of the immune system release factors that act in a hormonal way eg cytokines Therefore what we learn about endocrinology can apply to other parts of the body as wellHormones are secreted into the blood by an endocrine gland and the hormone is transported by the blood to a distant target siteNEUROENDOCRINE SIGNALINGSignals from the brain transmitted to the hypothalamus lead to release from the hypothalamus neuronal tissue of hormones which travel down system of blood vessels and eventually impinge upon pituitary cells and hormones released signal the release of pituitary hormonesAnterior pituitary is endocrine and the posterior pituitary is neuronalsee picture in slides
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